Actos and Avandia(2)

Ashley Davis
Contributor
Posted by Ashley DavisMay 28, 2009 6:13 PM
Tags: None

The FDA has recently announced that there will now be a “Black Box” warning on the Type 2 diabetes medications Actos and Avandia due to their connection to increased risks of heart attacks and heart-related deaths. If you have taken or been prescribed Avandia or Actos, you may be at risk.

Type 2 diabetes is a very serious and potentially life threatening disease which affects about 18-20 million Ameicans. It is also the leading cause of coronary heart disease, blindness, kidney failure and limb amputation.

The increased warning advises health care professionals to be more cautious in checking for signs of heart failure in their type 2 patients who have taken Avandia or Actos. Negative side effects associated with these drugs are:

  • Excessive, rapid weight gain
  • Shortness of breath
  • Swelling of the extremeties or organs

If you or someone you know has taken Avandia or Actos and are experiencing any of these symptoms, then contact your physician immediately and be aware of the risks.

3 Comments

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jibber
Posted by jibber
June 02, 2009 6:25 PM

I would like to point out that your article is highly misleading. Actos and Avandia have different outcomes with regards to cardiovascular mortality.
Actos has actually been proven to reduce deaths from cardiovascular endpoints in the PROactive study, a large randomised controlled trial in patients with existing cardiovascular disease and diabetes. Avandia, on the other hand has shown in a number of meta analases to increase death and numbers of heart attacks. Therefore Avandia has much stronger FDA warnings associated with it than Actos.
Your article seems to confuse the fact that Heart attacks are different from heart failure. The black box warning is on both products because of the increased risk of heart failure. However, no evidence has shown an increase in death due to heart failure.

Kongphop
Posted by Kongphop
June 02, 2009 6:45 PM

I was put on Actos approx 1 yr ago and ate the same amount as always and I went from 234 lbs to 280 lbs very quickly. My Dr. doubled my water pill and within 7 days I lost 14 lbs of water. I was on the verge of congestive heart failure, according to the Doctor. I became weak and had a hard time breathing. Five days ago I went to the E/R and was put into the hosp for 4 days for a cath and observed for 3 more days. I also know that I have taken Avandia before and have checked with Pharmacies trying to locate when I was perscribed Avanida and by whom and can't find it. I know I was perscribed this drug for Type II. Any ideas on how I could find that out. Avandia should know but I'm sure they would never devolge that information. Any help would be appreciated. Thanks, Konghhop

Kongphop
Posted by Kongphop
June 02, 2009 6:45 PM

I was put on Actos approx 1 yr ago and ate the same amount as always and I went from 234 lbs to 280 lbs very quickly. My Dr. doubled my water pill and within 7 days I lost 14 lbs of water. I was on the verge of congestive heart failure, according to the Doctor. I became weak and had a hard time breathing. Five days ago I went to the E/R and was put into the hosp for 4 days for a cath and observed for 3 more days. I also know that I have taken Avandia before and have checked with Pharmacies trying to locate when I was perscribed Avanida and by whom and can't find it. I know I was perscribed this drug for Type II. Any ideas on how I could find that out. Avandia should know but I'm sure they would never devolge that information. Any help would be appreciated. Thanks, Konghhop

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